ZYMESSENCE®

It's impossible to do label comparisons and know which systemic enzyme product will actually work when ingested. And, here's why: Due to differences in:

1. 1. Who a company gets its enzyme raw materials from (this is a super important point to ensure active enzymes are put into a product).
   2. How those raw materials were fermented and/or extracted by the maker.
   3. How they and the receiving company store its enzymes as raw materials.
   4. If they stabilize the enzymes or not, stabilization means putting the enzymes to "sleep" in suspended animation; (this is SUPER DUPER IMPORTANT to keep enzymes "alive" and "active". Unfortunately, most enzyme making firms and enzyme packaging firms have ZERO idea on how to stabilize an enzyme to keep it from becoming 'awake' and 'active' before ingestion. If the enzymes become active while in the pill or capsule, the enzymes will eat each other and then themselves; degrading the overall enzymatic activity of the product before you get to take it!!!!)
   5. The speed at which the different enzymes were blended together and then tableted or encapsulated, (faster = heat = enzyme death).
   6. The humidity and temperature in the plant during the above mentioned operations and during storage.
   7. Finally, if any enteric coatings or enteric matrixing is done, which enteric protective material is used and how much is used.

All these factors have a bearing on how well an enzyme product works when taken. AND, those factors are more important than what the label states was thrown into the mixer at the time of blending.

This is why of the nearly 100+ systemic enzyme products in the US market today, only a handful actually have a physiological action in the body when taken.

In the end, it's as Dr. Wong is notorious for saying:

"The proof of the pudding is in the eating!"

Of all the proteolytic enzymes, it's the only one that doesn't have a feedback mechanism to let it know when to stop lysing, (i.e. eating) blood proteins. This can cause an over-thinning of the blood and negatively affect blood clotting.
 
In nature nattokinase is always found with Vitamin K1 and that prevents the blood from becoming overly thin when eating the natto curd and taking in the nattokinase enzyme. When the nattokinase is extracted from that curd, the Vitamin K is left behind. So, of all the proteolytic enzymes it is the one most likely to create the danger of overly thin blood and cause hemorrhagic bleeding issues. We've spoken to two docs, one of whom is a very famous alternative doc, who got both themselves and their patients in bleeding trouble by using what were modest dosing levels of nattokinase. So, again, this is why there is NO nattokinase in any of our products!

You can read more about Nattokinase in Dr. Wong's blog post: Nattokinase: A Proteolytic Enzyme

Any systemic enzyme product whose label tells you the milligram amount of any enzyme in a product is not telling you anything. Enzymes are measured by activity not milligrams. All enzymes as raw materials come in strengths, stronger and weaker versions of the same enzyme (i.e. industrial grade, the various food grades vs pharmaceutical grade). For example, the extract potency for Pancreatin starts with a 10x - 12x now being the strongest available and 4x being relatively weak. You can have one milligram of a particular enzyme with 100,000 units of activity while 100mg of the same enzyme from a different enzyme maker might have only 50 units of activity. So, milligram measurements tell you nothing about the strength of an enzyme. Zymessence® uses only the top strength enzymes in its blend!

While the enzymes that go into a blending machine might have a particular amount of activity when fresh, if the blending and tableting process is not done correctly for enzymes the enzymatic activity of the finished product will be less due to the process having inactivated (killed) the enzymes.

Product makers who don't actually take and use their own products have ZERO idea as to whether any particular product actually works or not. Don't rely on sales staff to tell you how well a product works. It's their job to tell you the stuff is great regardless of how dead and useless it might be. Remember that most of the sales personnel in the nutritional industry are not health professionals nor are they the health minded folks that those in the health food stores might be; for them it's a job, selling vitamins or used cars or furniture it's all the same.

Everything we build at WAM Essentials, Inc. we personally use. We're the first ones to know whether a product actually works or not. We have no sales staff here, just customer service representatives to take customer orders. No one works on commission, no one answering the phone gives off the wall false claim answers on a products abilities or health advice. We don't sell anything that we don't think works and we get rid of products that give us less-than-desired results or we revise the products if we feel we can make the formula work better (new data always helps us here).

You can read more about this topic on a DWE Blog post: Systemic Enzymes: Milligrams vs Units of Activity

As an actual manufacturer of supplements and not just a company that has products made by others via contract manufacturing, I can state categorically that it is impossible to encapsulate or tablet herbs, vitamins, or enzymes without flow agents. Those materials (especially enzymes and some herbs) are too sticky and the machinery does not exist that can blend, tablet or encapsulate those sticky substances without making them un-sticky!!!

The products used as flow agents are the same products used in baking to keep batter from sticking to pans and paper cake cups! The agents are used in supplements are edible, pharmaceutical grade, (meaning they are of the highest grade of purity) and have zero physiological effect.

Anyone telling you their products are completely from of flow agents (aka excipients, etc) either does not know what their contract manufacturer really put into their product or they are telling you a bold face lie!

Sad fact is that if you have any encapsulated or tableted product claiming to be free of excipients, flow agents, etc, if independently tested, all will be found to contain them. Contract manufacturers lie to their clients as to their ability to build products without flow agents. One very well known doctor who first led the campaign for flow agent free supplements became very quiet about that issue just before her death when she found out that the contract manufacturer she had used for years had been woefully less than truthful in telling her what they made for her wasn't flow agent free.  

We looked into switching to rice bran when we began our own manufacturing in 2012. So, we contacted one of the primary suppliers of rice bran. According to the main makers of rice starch, if they know that a company intends to use the starch in nutritional supplements they won't sell the starch to them. Why?

Rice starch breeds bacteria. If a "kill step" (ie: cooking or baking the starch) isn't done then the bacteria can easily develop and grow on the starch and then in the supplement product. This discovery came from a recall of Nestle Toll House Cookie Dough in 2009 where rice bran was used to powder the outside of the roll of dough to prevent it sticking to the wrapping. As usually happens during the process of cookie making, children and adults will eat some of the uncooked dough. By June 27, 2009 the CDC had found that the dough, or more specifically the rice starch on the dough had caused 71 illnesses in 30 states with 28 individuals needing hospitalization for E-coli infections.

So, we've chosen to use maltodextrin as it's:

• more efficient and
• infintely safer to use because it doesn't naturally breed bacteria and
• use in pharmacology for 100+ years has shown it to be safe when ingested.

That's a good question. Dr. Wong formulated Zymessence:

• with the strongest proteolytic enzymes he could find
• and he included them in quantities that have a physiological action (meaningful and beneficial quantities so you can feel them working).
• just because it's an herb doesn't mean it's safe. Some of the herbs included in other proteolytic (systemic) enzyme blends can have the same harmful effects as pharmaceutical blood thinners or over the counter NSAIDS. Whereas the proteolytic enzymes we use in our Zymessence® have no LD 50 so they're safe to use (with the one exception that anyone on prescription blood thinners need to be monitored closely by their physician if they use any proteolytic enzyme).

It is possible to have so many ingredients in a supplement that not one of them is in the product in a meaningful amount to have a beneficial effect on the body. Dr. Wong wrote a blog post about just it and you can read it here: Nutritional Supplements with Everything But the Kitchen Sink

In the event that you receive your package and it is missing an item or includes an incorrect items, we must be contacted within three (3) business days of receipt of the package for resolution/ answers. No refund/return can be issued if more than three (3) business days pass without an attempt to contact us.

If you have a questions about packing (ie: safety seals, mfg vs expiration dates, lid liners, etc), we must be contacted within three (3) business days of receipt of the package for resolution/ answers. No refund/return can be issued if more than three (3) business days pass without an attempt to contact us.

Please see below for the most commonly asked questions about Zymessence®. We will continually add more FAQs to this as questions come in to us.